SCHEMBL19001664

SCHEMBL19001664

Cc1ccc2ccc3cnc4ccccc4c3c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.51
KDM4E B2RXH2 2/20 0.47
GPR3 P46089 1/20 0.47
MAOA P21397 1/20 0.45
CYP1A2 P05177 2/20 0.44
NQO2 P16083 1/20 0.43
CYP2A6 P11509 2/20 0.42
HTT P42858 2/20 0.41
MAPK1 P28482 2/20 0.41
TYMS P04818 1/20 0.40
EGFR P00533 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TOP2A P11388 2/20 0.39
HIF1A Q16665 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NR1I2 O75469 1/20 0.39
AHR P35869 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18266918 0.84 GPR3 (0.62) PDPK1KDM4EGPR3MAOACYP1A2
SCHEMBL159417 0.82 KDM4E (0.63) PDPK1KDM4EGPR3CYP1A2CYP2A6
Ammonia Solution, Strong SCHEMBL28354795 0.80 KDM4E (0.61) PDPK1KDM4EGPR3CYP1A2CYP2A6
SCHEMBL840612 0.77 KDM4E (0.62) KDM4EGPR3MAOACYP1A2NQO2
SCHEMBL18266925 0.77 GPR3 (0.62) PDPK1KDM4EGPR3MAOACYP1A2
SCHEMBL29808357 0.77 KDM4E (0.62) PDPK1KDM4EGPR3MAOACYP1A2
SCHEMBL28054044 0.77 KDM4E (0.62) PDPK1KDM4EGPR3MAOACYP1A2
SCHEMBL597413 0.76 CYP1A2 (0.57) MAOACYP1A2CYP2A6MAPK1ALDH1A1
SCHEMBL18907197 0.76 PDPK1 (0.54) PDPK1KDM4EGPR3CYP1A2NQO2
SCHEMBL2048246 0.75 PDPK1 (0.47) PDPK1KDM4EGPR3CYP1A2TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179396-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed