SCHEMBL19001701

SCHEMBL19001701

Brc1cccc2c1-c1ccccc1C21c2ccccc2-c2ccc(-c3ccccc3-c3ccccc3)cc21

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 18/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
RARB P10826 1/20 0.32
RARG P13631 1/20 0.32
RXRA P19793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15840175 0.93 PDK2 (0.46) PDK2ALDH1A1MAPK1
SCHEMBL15840172 0.93 PDK2 (0.46) PDK2ALDH1A1MAPK1
SCHEMBL19001702 0.93 PDK2 (0.46) PDK2ALDH1A1MAPK1
SCHEMBL19001904 0.91 PDK2 (0.42) PDK2ALDH1A1MAPK1RARBRARG
SCHEMBL19001985 0.90 PDK2 (0.43) PDK2ALDH1A1MAPK1
SCHEMBL16810810 0.86 PDK2 (0.42) PDK2ALDH1A1MAPK1
SCHEMBL16810777 0.86 PDK2 (0.42) PDK2ALDH1A1MAPK1
SCHEMBL23222875 0.85 PDK2 (0.44) PDK2
SCHEMBL23222874 0.85 PDK2 (0.40) PDK2ALDH1A1MAPK1
SCHEMBL19001692 0.85 PDK2 (0.44) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390365-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-14 EP disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed