Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687337 | 0.97 | PDK2 (0.43) | PDK2PGRAKR1A1AKR1B1TDP2 | |
| SCHEMBL19001700 | 0.92 | PDK2 (0.39) | PDK2PGRAKR1A1AKR1B1TDP2 | |
| SCHEMBL15840172 | 0.92 | PDK2 (0.46) | PDK2 | |
| SCHEMBL19001702 | 0.92 | PDK2 (0.46) | PDK2 | |
| SCHEMBL15840175 | 0.92 | PDK2 (0.46) | PDK2 | |
| SCHEMBL19001688 | 0.91 | PDK2 (0.47) | PDK2AKR1A1AKR1B1 | |
| SCHEMBL19001693 | 0.90 | PDK2 (0.42) | PDK2AKR1A1AKR1B1 | |
| SCHEMBL19001985 | 0.90 | PDK2 (0.43) | PDK2 | |
| SCHEMBL20687347 | 0.88 | PDK2 (0.40) | PDK2AKR1A1AKR1B1 | |
| SCHEMBL21102598 | 0.87 | PDK2 (0.39) | PDK2PGRAKR1A1AKR1B1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390365-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20200212301-A1 | SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
| WO-2019020654-A1 | SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-01-31 | — | — | WO | disclosed |
| WO-2017102063-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200212301-A1 | SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES | SELE, KCNB2, SCNN1B | PDK2 382/4885PGR 1276/4885AKR1A1 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.