SCHEMBL19001824

SCHEMBL19001824

c1ccc(-c2ccc3c(c2)C2(c4ccccc4-3)c3ccccc3-c3c(N4c5ccccc5Sc5ccccc54)cccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 17/20 0.39
BCHE P06276 1/20 0.34
PDE6D O43924 1/20 0.32
TYMS P04818 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23278308 0.91 PDK2 (0.32) PDK2
SCHEMBL15213624 0.90 PDK2 (0.35) PDK2BCHEPDE6DTYMS
SCHEMBL22183041 0.89 PDE6D (0.37) PDK2BCHEPDE6D
SCHEMBL23278272 0.88 BCHE (0.30) BCHE
SCHEMBL24648264 0.87 MAOA (0.38) BCHE
SCHEMBL10039058 0.85 PDK2 (0.40) PDK2BCHEPDE6D
SCHEMBL23278289 0.85 HDAC6 (0.36)
SCHEMBL19001815 0.84 PDK2 (0.39) PDK2PDE6DTYMS
SCHEMBL19001828 0.84 PDK2 (0.39) PDK2PDE6DTYMS
SCHEMBL19001818 0.84 PDK2 (0.39) PDK2PDE6DTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390365-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-14 EP disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed