Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389131 | 0.89 | GPR119 (0.66) | GPR119CYP2C9KCNH2 | |
| SCHEMBL5649951 | 0.83 | GPR119 (0.53) | GPR119CYP2C9KCNH2SMN1; SMN2HPGD | |
| SCHEMBL386717 | 0.75 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| SCHEMBL386516 | 0.75 | GPR119 (0.71) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390951 | 0.73 | GPR119 (0.68) | GPR119CYP2C9KCNH2SMN1; SMN2ALDH1A1 | |
| SCHEMBL389954 | 0.73 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389429 | 0.72 | GPR119 (0.69) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390804 | 0.72 | GPR119 (0.69) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390160 | 0.72 | GPR119 (0.69) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1070471 | 0.72 | GPR119 (0.64) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322152-A1 | Method of preparing a composition comprising a GPR119 agonist | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |