Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23310456 | 0.83 | ESR1 (0.44) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8984806 | 0.81 | MAPT (0.57) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20414401 | 0.78 | SMN1; SMN2 (0.53) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5492754 | 0.77 | MEN1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4258846 | 0.77 | MEN1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14353392 | 0.77 | MEN1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL15283118 | 0.77 | MEN1 (0.62) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL19002147 | 0.76 | MEN1 (0.52) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14122566 | 0.75 | MEN1 (0.71) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL30516188 | 0.75 | MEN1 (0.71) | MAPTMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170175078-A1 | CELL CULTURE SUBSTRATE COMPRISING FLUORINE-CONTAINING POLYMER ON ITS SURFACE | NIPPON SHOKUBAI, CO., LTD. (JP) | 2017-06-22 | — | — | US | disclosed |