SCHEMBL19002147

SCHEMBL19002147

COCc1ccc(C2(c3ccc(COC)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
OPRK1 P41145 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
PDK2 Q15119 6/20 0.50
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
POLB P06746 1/20 0.37
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34
PDE4D Q08499 1/20 0.33
MDM2 Q00987 4/20 0.32
TP53 P04637 3/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26257703 0.90 PDK2 (0.43) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL13497452 0.86 LMNA (0.50) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL26257701 0.84 PDK2 (0.50) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL13497453 0.83 LMNA (0.47) MEN1KMT2AMAPTLMNAPDK2
SCHEMBL20795883 0.81 PDK2 (0.50) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL3423319 0.81 PDK2 (0.50) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL8984806 0.79 MAPT (0.57) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL973220 0.77 MEN1 (0.46) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL19002162 0.76 MAPT (0.53) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL20414401 0.76 SMN1; SMN2 (0.53) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760712-B2 Triarylmethane compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-19 US disclosed
US-20170175078-A1 CELL CULTURE SUBSTRATE COMPRISING FLUORINE-CONTAINING POLYMER ON ITS SURFACE NIPPON SHOKUBAI, CO., LTD. (JP) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760712-B2 Triarylmethane compounds CBR3, HAX1, HRH3 MEN1 3609/4885KMT2A 642/4885MAPT 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.