Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19049022 | 0.88 | SLC6A2 (0.44) | SLC6A2SLC6A4HTR1AKMT2AALDH1A1 | |
| SCHEMBL18997340 | 0.84 | HTR1A (0.43) | SLC6A2SLC6A4HTR1AKMT2AALDH1A1 | |
| SCHEMBL19049024 | 0.84 | HTR1A (0.43) | SLC6A2SLC6A4HTR1AKMT2AALDH1A1 | |
| SCHEMBL20697220 | 0.77 | IDO1 (0.45) | SLC6A2SLC6A4KMT2AALDH1A1HTT | |
| SCHEMBL29198738 | 0.77 | SLC6A2 (0.55) | SLC6A2SLC6A4HTR1AKMT2AALDH1A1 | |
| SCHEMBL21246154 | 0.73 | MKNK2 (0.44) | SLC6A2SLC6A4GRM5IDO1 | |
| SCHEMBL18997352 | 0.73 | PDE10A (0.44) | SLC6A2SLC6A4HTR1AKMT2AALDH1A1 | |
| SCHEMBL21258513 | 0.72 | IDO1 (0.41) | ALDH1A1L3MBTL1LMNAGRM5NPC1 | |
| SCHEMBL8508286 | 0.71 | GRM5 (0.51) | KMT2AHTTGRM5MEN1TSHR | |
| SCHEMBL29512293 | 0.70 | MAPT (0.70) | KMT2AALDH1A1HTTALOX12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | SLC6A2 4742/4885SLC6A4 4710/4885HTR1A 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.