Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17348254 | 0.87 | CNR2 (0.33) | MAPTPOLBHTTALDH1A1KMT2A | |
| SCHEMBL17343555 | 0.87 | MAPT (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL20506766 | 0.77 | MEN1 (0.42) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL20499799 | 0.76 | F13A1 (0.39) | MAPTPOLBALDH1A1KMT2AMAPK1 | |
| SCHEMBL145821 | 0.75 | CYP2C19 (0.50) | MAPTPOLBHTTALDH1A1MAPK1 | |
| SCHEMBL19646065 | 0.75 | APP (0.46) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL20506762 | 0.72 | ALDH1A1 (0.33) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL21707451 | 0.70 | MEN1 (0.37) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL17689350 | 0.70 | ALDH1A1 (0.46) | MAPTHTTALDH1A1KMT2AMAPK1 | |
| SCHEMBL7637421 | 0.70 | MAPT (0.52) | MAPTPOLBHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173170-A1 | METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173170-A1 | METHODS AND MATERIALS FOR THERAPEUTIC DELIVERY | PAICS, PHPT1, MAPT | MAPT 3/4885POLB 1233/4885HTT 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.