SCHEMBL19002943

SCHEMBL19002943

c1ccc(P(Cc2ccccc2-c2cc(CP(c3ccccc3)c3ccccc3)c(-c3ccccc3CP(c3ccccc3)c3ccccc3)cc2CP(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTGER1 P34995 1/20 0.31
PTGER4 P35408 1/20 0.31
PTGER3 P43115 1/20 0.31
PTGER2 P43116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720169 0.92 CYP3A4 (0.38) DPP4CYP3A4TDP1PTGER1PTGER4
Potassium SCHEMBL30843013 0.90 CYP3A4 (0.36) DPP4CYP3A4TDP1PTGER1PTGER4
SCHEMBL29695439 0.90 CYP3A4 (0.36) DPP4CYP3A4TDP1PTGER1PTGER4
Phosphine SCHEMBL29173742 0.90 CYP3A4 (0.36) DPP4CYP3A4TDP1PTGER1PTGER4
Lithium SCHEMBL29695298 0.90 CYP3A4 (0.36) DPP4CYP3A4TDP1PTGER1PTGER4
Bromide SCHEMBL30945893 0.88 CYP3A4 (0.35) DPP4CYP3A4TDP1
SCHEMBL19002937 0.85 CSNK2A2 (0.30)
SCHEMBL30945894 0.84 DPP4 (0.32) DPP4CYP3A4TDP1
SCHEMBL8522187 0.82 DPP4 (0.52) DPP4PTGER1PTGER4PTGER3PTGER2
SCHEMBL8029937 0.81 FFAR1 (0.38) CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641824-B Stable hydroformylation catalyst for producing high normal/isomerization ratio aldehyde product 伊士曼化工公司 2022-12-20 CN disclosed
EP-3507269-B1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT EASTMAN CHEM CO (US) 2020-09-23 EP disclosed
US-9687837-B1 Stable hydroformylation catalyst for preparation of high N/Iso ratio aldehyde product EASTMAN CHEMICAL COMPANY (US) 2017-06-27 US disclosed