Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720169 | 0.88 | CYP3A4 (0.38) | PDCD1CD274CYP3A4KMT2ATDP1 | |
| SCHEMBL8056038 | 0.88 | CTBP2 (0.32) | FFAR1FFAR4HTR7TAAR1PDCD1 | |
| Phosphine SCHEMBL29173742 | 0.86 | CYP3A4 (0.36) | PDCD1CD274CYP3A4KMT2ATDP1 | |
| Lithium SCHEMBL29695298 | 0.86 | CYP3A4 (0.36) | PDCD1CD274CYP3A4KMT2ATDP1 | |
| Potassium SCHEMBL30843013 | 0.86 | CYP3A4 (0.36) | PDCD1CD274CYP3A4KMT2ATDP1 | |
| SCHEMBL29695439 | 0.86 | CYP3A4 (0.36) | PDCD1CD274CYP3A4KMT2ATDP1 | |
| Bromide SCHEMBL30945893 | 0.84 | CYP3A4 (0.35) | PDCD1CD274CYP3A4TDP1 | |
| SCHEMBL6678983 | 0.84 | TAAR1 (0.43) | TAAR1NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL8624095 | 0.81 | MCL1 (0.35) | MCL1TSHRALDH1A1HPGDCYP1A2 | |
| SCHEMBL30945894 | 0.81 | DPP4 (0.32) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695756-B1 | Process for the preparation of compounds of the phosphane series as well as their use | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-5728886-A | Compounds of the phosphine group, their preparation and their use | HOECHST AG (DE) | 1998-03-17 | — | — | US | disclosed |
| EP-0695756-A1 | Compounds of the phosphane series, process for their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |