Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL9169420 | 0.80 | APOBEC3G (0.39) | MAPTL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| Zinc Ion SCHEMBL6391833 | 0.71 | CYSLTR2 (0.36) | CETP | |
| SCHEMBL10354348 | 0.71 | HPGD (0.42) | HPGDALDH1A1MAPTTDP1RAB9A | |
| SCHEMBL57312 | 0.70 | ACHE (0.53) | ALDH1A1MAPTTDP1TSHR | |
| SCHEMBL29468536 | 0.70 | ACHE (0.53) | ALDH1A1MAPTTDP1TSHR | |
| SCHEMBL29411690 | 0.70 | ACHE (0.53) | ALDH1A1MAPTTDP1TSHR | |
| Zinc Ion SCHEMBL5692556 | 0.70 | PPARA (0.41) | MAPTCETPKDM4E | |
| SCHEMBL4231323 | 0.68 | ACHE (0.50) | ALDH1A1MAPTTDP1TSHR | |
| SCHEMBL9067022 | 0.66 | ACHE (0.47) | HPGDALDH1A1MAPTTDP1TSHR | |
| SCHEMBL10702121 | 0.66 | ACHE (0.47) | HPGDALDH1A1MAPTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688646-B2 | Process for producing N-methyl or N,N-dimethyl amines | Lanxhou Institute of Chemical Physics, Chinese Academy of Sciences (CN) | 2017-06-27 | — | — | US | disclosed |