Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.81 |
| ▸ | MEN1 | O00255 | 12/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.81 |
| ▸ | LMNA | P02545 | 8/20 | 0.81 |
| ▸ | HTT | P42858 | 6/20 | 0.81 |
| ▸ | NPC1 | O15118 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.69 |
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | MITF | O75030 | 7/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484460 | 0.87 | MAPT (0.77) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL3484458 | 0.87 | MAPT (0.77) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19003455 | 0.87 | MAPT (0.77) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19003457 | 0.84 | MAPT (0.72) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19003234 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL13113131 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19003465 | 0.79 | MAPT (0.65) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19003250 | 0.79 | MAPT (0.51) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL29530846 | 0.76 | MAPT (0.75) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL19003275 | 0.75 | KMT2A (0.48) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |