⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008155 | 1.00 | — | — | |
| SCHEMBL1904497 | 1.00 | — | — | |
| SCHEMBL3860149 | 0.94 | — | — | |
| SCHEMBL3860150 | 0.94 | — | — | |
| SCHEMBL3859861 | 0.92 | — | — | |
| SCHEMBL3859856 | 0.92 | — | — | |
| SCHEMBL3862161 | 0.89 | ACHE (0.32) | — | |
| SCHEMBL3868647 | 0.89 | ACHE (0.32) | — | |
| SCHEMBL3868644 | 0.89 | ACHE (0.32) | — | |
| SCHEMBL3862157 | 0.89 | ACHE (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006272-A1 | β-GLUCURONIDE LINKER-PAYLOADS, PROTEIN CONJUGATES THEREOF, AND METHODS THEREOF | SUTRO BIOPHARMA, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2023158305-A1 | MASKED IL12 PROTEIN | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023077126-A1 | TRANS-CYCLOOCTENE CONJUGATES | TAMBO, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2020256544-A1 | TETRAZINES FOR HIGH CLICK RELEASE SPEED AND YIELD | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |
| WO-2017106427-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | FOX JOSEPH (US) | 2017-06-22 | — | — | WO | disclosed |