SCHEMBL1900402

SCHEMBL1900402

C=C(C)C(=O)NC(C)(CC(C)=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP3A4 P08684 3/20 0.42
CYP1A2 P05177 1/20 0.42
RECQL P46063 1/20 0.42
CYP2C19 P33261 3/20 0.42
HIF1A Q16665 1/20 0.42
MAPK1 P28482 1/20 0.41
CYP2C9 P11712 3/20 0.38
CTSA P10619 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11598275 0.88 CYP3A4 (0.42) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL5057247 0.81 CYP3A4 (0.40) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL10634824 0.80 CYP1A2 (0.39) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL10634832 0.80 CYP3A4 (0.39) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL11596734 0.77 CYP3A4 (0.40) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL732705 0.76 ALDH1A1 (0.50) ALDH1A1KDM4ECYP1A2RECQLCYP2C19
SCHEMBL6906467 0.76 KDM4E (0.55) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL5199578 0.74 ALDH1A1 (0.36) ALDH1A1KDM4ECYP3A4CYP1A2RECQL
SCHEMBL1144525 0.73 CYP2C19 (0.56) ALDH1A1CYP3A4CYP1A2RECQLCYP2C19
SCHEMBL11596850 0.73 CYP3A4 (0.46) ALDH1A1KDM4ECYP3A4CYP1A2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686321-B2 MIXTURE; LUBRICANT OIL ADDITIVE CASTROL LIMITED (GB) 2004-02-03 US claimed
US-10754249-B2 Coating compositions for photolithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-08-25 US disclosed
CN-110488571-A Coating composition for photoetching ROHM & HAAS ELECT MAT 2019-11-22 CN disclosed
US-20170285478-A1 COATING COMPOSITIONS FOR PHOTOLITHOGRAPHY ROHM AND HAAS ELECTRONIC MATERIALS LLC 2017-10-05 US disclosed
US-9690199-B2 Coating compositions for photolithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-06-27 US disclosed
US-20170030015-A1 POLYMER COMPOSITION AND PROCESS FOR MAKING THE SAME ARON UNIVERSAL LTD. (IN) 2017-02-02 US disclosed
EP-3124553-A1 POLYMER COMPOSITION AND PROCESS FOR MAKING THE SAME Aron Universal Ltd (IN) 2017-02-01 EP disclosed
US-20160223911-A1 COATING COMPOSITIONS FOR PHOTOLITHOGRAPHY ROHM & HAAS ELECT MAT (US) 2016-08-04 US disclosed
US-9323154-B2 Coating compositions for photolithography ROHM AND HAAS ELECTRONIC MATERIALS, LLC (US) 2016-04-26 US disclosed
EP-1209528-B1 Photoresist composition ETERNAL TECHNOLOGY CORP (US) 2015-07-22 EP disclosed
EP-0193272-A2 Preparation of a graft-copolymeric compatibilizer useful as an oil additive ROHM AND HAAS COMPANY (US) 1986-09-03 EP disclosed
EP-0171167-A2 Process for preparation of oil compositions comprising a viscosity index improver-dispersant additive EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-02-12 EP disclosed
EP-0026613-B1 METHOD OF GRAFTING EPM AND EPDM POLYMERS COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1984-11-21 EP disclosed
US-4464493-A Process for dissolving EPM and EPDM polymers in oil COPOLYMER RUBBER & CHEMICAL CORP. (US) 1984-08-07 US disclosed
US-4434064-A GRINDING WITH OXYGEN ATLANTIC RICHFIELD COMPANY (US) 1984-02-28 US disclosed
US-4417991-A NONTHICKENING, EXTREME PRESSURE LUBRICANTS ATLANTIC RICHFIELD COMPANY (US) 1983-11-29 US disclosed
US-4340689-A Method of grafting EPM and EPDM polymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1982-07-20 US disclosed
EP-0026613-A1 Method of grafting EPM and EPDM polymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1981-04-08 EP disclosed
US-4251644-A Polar resins having improved characteristics by blending with EPM and EPDM polymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1981-02-17 US disclosed
US-4146489-A LUBRICANTS, DISPERSANTS ROHM AND HAAS COMPANY (US) 1979-03-27 US disclosed