Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22335040 | 1.00 | KDM1A (0.49) | KDM1ARCOR1HTR2CTSHRMAOB | |
| SCHEMBL14643863 | 0.81 | KDM1A (0.44) | KDM1ARCOR1HTR2CTSHRMAOB | |
| SCHEMBL23995555 | 0.81 | HTR2C (0.43) | KDM1AHTR2CALDH1A1HTR2AHTR2B | |
| SCHEMBL18998726 | 0.79 | KDM1A (0.47) | KDM1ARCOR1TSHRMAOBALDH1A1 | |
| SCHEMBL18998470 | 0.79 | KDM1A (0.47) | KDM1ARCOR1TSHRMAOBALDH1A1 | |
| SCHEMBL12875677 | 0.79 | KDM1A (0.47) | KDM1ARCOR1TSHRMAOBALDH1A1 | |
| SCHEMBL23995535 | 0.79 | HTR2C (0.69) | KDM1AHTR2CMAOBHTR2AHTR2B | |
| SCHEMBL16591278 | 0.79 | HTR2C (0.69) | KDM1AHTR2CMAOBHTR2AHTR2B | |
| SCHEMBL23993580 | 0.77 | HTR2C (0.67) | KDM1ARCOR1HTR2CMAOBHTR2A | |
| SCHEMBL15767785 | 0.77 | HTR2C (0.67) | KDM1ARCOR1HTR2CMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174713-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174713-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | TBKBP1, TNKS1BP1, TNKS | KDM1A 2010/4885RCOR1 1638/4885HTR2C 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.