SCHEMBL19004981

SCHEMBL19004981

Oc1ccc(-c2ccc3nc(Nc4cc(CN5CCNCC5)ccn4)[nH]c3c2)cn1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBK1 Q9UHD2 20/20 0.68
IKBKE Q14164 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19004897 0.89 TBK1 (0.75) TBK1IKBKE
SCHEMBL19004945 0.89 TBK1 (0.73) TBK1IKBKE
Hydrochloric Acid SCHEMBL20720956 0.88 TBK1 (0.72) TBK1IKBKE
Hydrochloric Acid SCHEMBL18986017 0.88 TBK1 (0.74) TBK1IKBKE
SCHEMBL19005181 0.88 TBK1 (0.73) TBK1IKBKE
Hydrochloric Acid SCHEMBL18985730 0.87 TBK1 (0.72) TBK1IKBKE
SCHEMBL19005001 0.87 TBK1 (0.72) TBK1IKBKE
SCHEMBL19005084 0.87 TBK1 (0.77) TBK1IKBKE
SCHEMBL19005046 0.87 TBK1 (0.75) TBK1IKBKE
SCHEMBL19004982 0.87 TBK1 (0.75) TBK1IKBKE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017102091-A1 HETEROARYLBENZIMIDAZOLE COMPOUNDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-06-22 WO disclosed