Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.68 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004980 | 0.91 | TBK1 (0.65) | TBK1IKBKEFLT3TMEM97RPS6KA6 | |
| SCHEMBL19005331 | 0.90 | TBK1 (0.80) | TBK1 | |
| Hydrochloric Acid SCHEMBL18985757 | 0.90 | TBK1 (0.79) | TBK1 | |
| SCHEMBL19005445 | 0.87 | TBK1 (0.85) | TBK1IKBKEFLT3TMEM97RPS6KA6 | |
| SCHEMBL19005140 | 0.85 | TBK1 (0.68) | TBK1IKBKE | |
| SCHEMBL19005150 | 0.85 | TBK1 (0.79) | TBK1IKBKEFLT3RPS6KA6 | |
| SCHEMBL19005009 | 0.83 | TBK1 (0.75) | TBK1IKBKEFLT3TMEM97RPS6KA6 | |
| SCHEMBL19005191 | 0.83 | TBK1 (0.76) | TBK1IKBKEFLT3TMEM97RPS6KA6 | |
| Hydrochloric Acid SCHEMBL20720921 | 0.82 | TBK1 (0.74) | TBK1IKBKEFLT3TMEM97RPS6KA6 | |
| Hydrochloric Acid SCHEMBL20721052 | 0.82 | TBK1 (0.75) | TBK1IKBKEFLT3TMEM97RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |