SCHEMBL19005519 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	HTR2C	P28335	13/20	0.38

▸	HTR2A	P28223	6/20	0.37

▸	NTRK1	P04629	1/20	0.37

▸	LTK	P29376	1/20	0.37

▸	TYRO3	Q06418	1/20	0.37

▸	NTRK2	Q16620	1/20	0.37

▸	CLK4	Q9HAZ1	1/20	0.37

▸	MCHR1	Q99705	1/20	0.35

▸	HTR1A	P08908	2/20	0.34

▸	PNMT	P11086	1/20	0.33

▸	HTR3E	A5X5Y0	1/20	0.33

▸	HTR3B	O95264	1/20	0.33

▸	HTR3A	P46098	1/20	0.33

▸	HTR3D	Q70Z44	1/20	0.33

▸	HTR3C	Q8WXA8	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19005543	0.74	MCHR1 (0.35)	HTR2CHTR2AMCHR1
SCHEMBL19005538	0.74	HTR2C (0.44)	HTR2CHTR2AMCHR1HTR1APNMT
SCHEMBL19005553	0.71	HTR2A (0.31)	HTR2CHTR2A
SCHEMBL29539173	0.70	HTR2A (0.50)	HTR2CHTR2AMCHR1HTR3A
SCHEMBL839815	0.70	HTR2A (0.50)	HTR2CHTR2AMCHR1HTR3A
SCHEMBL19005523	0.70	MCHR1 (0.37)	HTR2CHTR2AMCHR1
SCHEMBL24187436	0.69	HTR2C (0.53)	HTR2CHTR2APNMT
SCHEMBL19005522	0.69	HRH4 (0.40)	HTR2CHTR2AMCHR1
Hydrochloric Acid SCHEMBL20139551	0.69	HTR2A (0.49)	HTR2CHTR2AMCHR1HTR3A
SCHEMBL19005524	0.69	MCHR1 (0.36)	HTR2CHTR2AMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017101796-A1	PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF	四川科伦博泰生物医药股份有限公司	2017-06-22	—	—	WO	disclosed