Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005522 | 0.70 | HRH4 (0.40) | HTR2AHTR2CHRH4WNT1GSK3B | |
| SCHEMBL22359272 | 0.70 | PI4KA (0.60) | — | |
| SCHEMBL19005561 | 0.69 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL19005553 | 0.69 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL1104770 | 0.68 | HTR2C (0.46) | HTR2AHTR2C | |
| SCHEMBL19005520 | 0.67 | HTR2A (0.35) | HTR2AHTR2CWNT1GSK3BDYRK1A | |
| SCHEMBL19005552 | 0.67 | MCHR1 (0.36) | HTR2AHTR2C | |
| SCHEMBL19005541 | 0.66 | MCHR1 (0.31) | HTR2AHTR2C | |
| SCHEMBL19005546 | 0.66 | MCHR1 (0.31) | HTR2AHTR2C | |
| SCHEMBL17687467 | 0.65 | GSK3B (0.36) | HTR2AHTR2CWNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |