SCHEMBL19005845

SCHEMBL19005845

CC(F)(F)c1nnc2n1CCNC2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.37
LIPG Q9Y5X9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13093275 0.86 MGLL (0.33) MGLL
SCHEMBL212149 0.86 MGLL (0.36) MGLLLIPG
Hydrochloric Acid SCHEMBL332198 0.84 MGLL (0.35) MGLLLIPG
SCHEMBL1971368 0.83 MGLL (0.34) MGLLLIPG
SCHEMBL19005247 0.83 MGLL (0.34) MGLL
Hydrochloric Acid SCHEMBL573084 0.81 MGLL (0.34) MGLL
SCHEMBL4244840 0.80 MGLL (0.31) MGLL
Hydrochloric Acid SCHEMBL3841448 0.76 DPP4 (0.33) MGLLLIPG
SCHEMBL929279 0.72 POLB (0.47) MGLL
SCHEMBL14955970 0.71 MGLL (0.34) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370125-A1 PHTHALAZINONE-BASED PARP-1 INHIBITORS Oregon Health and Science University (US) 2024-05-22 EP disclosed
WO-2017101796-A1 PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2017-06-22 WO disclosed