Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | F7 | P08709 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207681 | 0.91 | MRGPRX4 (0.46) | HPGDSMN1; SMN2RAB9ANPC1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL2599577 | 0.90 | MRGPRX4 (0.45) | HPGDSMN1; SMN2RAB9ANPC1MRGPRX4 | |
| SCHEMBL8106269 | 0.83 | CA12 (0.43) | HPGDLMNASMN1; SMN2NPC1EGFR | |
| SCHEMBL9220687 | 0.82 | CHRM2 (0.43) | HPGDSMN1; SMN2RAB9ANPC1MRGPRX4 | |
| SCHEMBL724361 | 0.81 | CCR5 (0.48) | LMNASMN1; SMN2RAB9A | |
| SCHEMBL1354912 | 0.80 | CHRM2 (0.53) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL1354913 | 0.80 | CHRM2 (0.53) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL10604975 | 0.79 | HPGD (0.56) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL1901761 | 0.75 | HPGD (0.42) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL7752289 | 0.75 | HPGD (0.42) | HPGDLMNASMPD1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323967-A2 | FESOTERODINE COMPRISING A REDUCED AMOUNT OF DEHYDROXYFESOTERODINE | Actavis Group PTC EHF (IS) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010010464-A2 | FESOTERODINE SUBSTANTIALLY FREE OF DEHYDROXY IMPURITY | ACTAVIS GROUP PTC EHF (IS) | 2010-01-28 | — | — | WO | disclosed |