Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005989 | 0.90 | HDAC1 (0.37) | CYP19A1CYP3A4SLC5A1SLC5A2MEN1 | |
| SCHEMBL18987395 | 0.90 | CHRM4 (0.37) | SLC5A1SLC5A2MEN1KMT2AHDAC1 | |
| SCHEMBL18987410 | 0.89 | CYP3A4 (0.41) | CYP3A4MEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL19005985 | 0.88 | HDAC1 (0.39) | CYP3A4SLC5A1SLC5A2MEN1KMT2A | |
| SCHEMBL18987304 | 0.88 | HDAC1 (0.39) | SLC5A1SLC5A2MEN1KMT2AHDAC1 | |
| SCHEMBL18987192 | 0.88 | CYP19A1 (0.44) | CYP19A1CYP3A4SLC5A1SLC5A2MEN1 | |
| SCHEMBL19005984 | 0.87 | HDAC1 (0.39) | SLC5A1SLC5A2MEN1KMT2AHDAC1 | |
| SCHEMBL18987302 | 0.86 | HDAC1 (0.38) | SLC5A1SLC5A2MEN1KMT2AHDAC1 | |
| SCHEMBL19005992 | 0.86 | HDAC1 (0.39) | CYP3A4MEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL19006008 | 0.83 | HDAC1 (0.36) | CYP3A4MEN1KMT2AHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |