Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005992 | 0.89 | HDAC1 (0.39) | HDAC1HDAC2POLBALDH1A1KMT2A | |
| SCHEMBL19005991 | 0.87 | MTNR1A (0.34) | HDAC1HDAC2POLBKMT2AMAPT | |
| SCHEMBL19005915 | 0.86 | PDE4A (0.33) | HDAC1HDAC2MAPTTSHRSMN1; SMN2 | |
| SCHEMBL19005989 | 0.84 | HDAC1 (0.37) | HDAC1HDAC2ALDH1A1KMT2AMAPT | |
| SCHEMBL19005969 | 0.83 | CYP19A1 (0.45) | HDAC1HDAC2KMT2AMAPTMEN1 | |
| SCHEMBL18987395 | 0.82 | CHRM4 (0.37) | HDAC1HDAC2ALDH1A1KMT2AMEN1 | |
| SCHEMBL18987410 | 0.81 | CYP3A4 (0.41) | HDAC1HDAC2ALDH1A1KMT2AMAPT | |
| SCHEMBL19005985 | 0.80 | HDAC1 (0.39) | HDAC1HDAC2ALDH1A1KMT2AMAPT | |
| SCHEMBL18987304 | 0.80 | HDAC1 (0.39) | HDAC1HDAC2ALDH1A1KMT2AMAPT | |
| SCHEMBL19006005 | 0.80 | HTR1A (0.34) | HDAC1HDAC2POLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |