SCHEMBL19006040

SCHEMBL19006040

c1ccc2c(c1)c1ccccc1c1cc(-c3ccc(-c4ccc5c6ccccc6c6nccn6c5c4)cc3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.35
TACR1 P25103 2/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
MAPK8 P45983 3/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
LIMK1 P53667 1/20 0.32
CHEK1 O14757 1/20 0.31
MAP4K4 O95819 1/20 0.31
CSF1R P07333 1/20 0.31
PRKACA P17612 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13309571 0.85 TACR1 (0.41) PTAFRTACR1PDE3BPDE3ACCNE1
SCHEMBL20368043 0.83 TACR1 (0.35) PTAFRTACR1PDE3BPDE3ACCNE1
SCHEMBL22280686 0.82 ESR1 (0.40) PDE3BPDE3ACCNE1CDK2GAA
SCHEMBL22280685 0.81 TNK2 (0.38) TACR1
SCHEMBL20368018 0.81 KDM4E (0.39) PTAFRTACR1MAPK8HTR3EHTR3B
SCHEMBL22281109 0.81 TNK2 (0.42)
SCHEMBL22280933 0.81 TNK2 (0.40) TACR1
SCHEMBL29636632 0.80 MAPK8 (0.41) TACR1PDE3BPDE3ACCNE1CDK2
SCHEMBL840406 0.80 MAPK8 (0.41) TACR1PDE3BPDE3ACCNE1CDK2
SCHEMBL841311 0.80 ALDH1A1 (0.36) TACR1PDE3BPDE3AMAPK8HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11617290-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-28 US disclosed
US-20170179403-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179403-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed