Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006145 | 0.91 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL19006158 | 0.91 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL19006157 | 0.91 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL19006298 | 0.91 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL19006152 | 0.87 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL18988737 | 0.87 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL18988735 | 0.87 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL19006151 | 0.86 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL19006153 | 0.85 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006148 | 0.85 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |