Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988384 | 0.92 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL18988551 | 0.86 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006197 | 0.84 | PIK3CD (0.61) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006194 | 0.83 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988646 | 0.81 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL19006249 | 0.79 | PIK3CD (0.67) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988709 | 0.79 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988759 | 0.78 | PIK3CD (0.61) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006301 | 0.77 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988694 | 0.77 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |