Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.66 |
| ▸ | RET | P07949 | 3/20 | 0.64 |
| ▸ | KIF5B | P33176 | 2/20 | 0.64 |
| ▸ | KDR | P35968 | 14/20 | 0.63 |
| ▸ | FLT1 | P17948 | 11/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.62 |
| ▸ | FLT4 | P35916 | 6/20 | 0.62 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280 | 0.90 | KDR (0.77) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL17520351 | 0.90 | KDR (0.78) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL19220777 | 0.90 | RET (0.67) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL17520325 | 0.87 | KDR (0.77) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL19220775 | 0.87 | RET (0.64) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL8789 | 0.82 | EGFR (0.84) | EGFRRETKIF5BKDRFLT4 | |
| SCHEMBL19006946 | 0.80 | EGFR (0.81) | EGFRRETKIF5BKDRFLT4 | |
| SCHEMBL13617351 | 0.80 | KDR (0.65) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL1887966 | 0.79 | KDR (0.71) | EGFRRETKIF5BKDRFLT1 | |
| SCHEMBL2102985 | 0.79 | EGFR (1.00) | EGFRKDRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181554-A1 | QUINAZOLINE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |