⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389593 | 0.91 | — | — | |
| SCHEMBL29883 | 0.91 | — | — | |
| SCHEMBL6651983 | 0.86 | MEN1 (0.33) | — | |
| SCHEMBL28157372 | 0.86 | — | — | |
| SCHEMBL14481257 | 0.82 | — | — | |
| SCHEMBL22139518 | 0.82 | TRPV1 (0.31) | — | |
| SCHEMBL6653698 | 0.80 | CES1 (0.30) | — | |
| Beta-Citronellene SCHEMBL9066753 | 0.80 | TSHR (0.40) | — | |
| SCHEMBL24111239 | 0.78 | LMNA (0.42) | — | |
| SCHEMBL23593919 | 0.78 | LMNA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934566-B1 | EXENDIN-4 DERIVATIVES AS DUAL GLP1/GIP OR TRIGONAL GLP1/GIP/GLUCAGON AGONISTS | SANOFI SA (FR) | 2017-06-21 | — | — | EP | disclosed |