⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL16266752 | 0.72 | TP53 (0.33) | — | |
| SCHEMBL28598183 | 0.67 | — | — | |
| SCHEMBL13716526 | 0.65 | — | — | |
| SCHEMBL3322626 | 0.64 | — | — | |
| SCHEMBL23260158 | 0.62 | — | — | |
| SCHEMBL20031203 | 0.62 | — | — | |
| Ammonia Solution, Strong SCHEMBL19501699 | 0.61 | — | — | |
| SCHEMBL33233 | 0.61 | — | — | |
| SCHEMBL13538948 | 0.61 | — | — | |
| SCHEMBL15033111 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029503-B2 | Method for native ligation of polypeptides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-05-12 | — | — | US | disclosed |
| EP-2493909-B1 | METHOD FOR NATIVE LIGATION OF POLYPEPTIDES | CENTRE NAT RECH SCIENT (FR) | 2014-05-21 | — | — | EP | disclosed |
| EP-2493909-A1 | METHOD FOR NATIVE LIGATION OF POLYPEPTIDES | Centre National De La Recherche Scientifique CNRS (FR) | 2012-09-05 | — | — | EP | disclosed |
| US-20120220721-A1 | Method for Native Ligation of Polypeptides | INSTITUT PASTEUR DE LILLE (FR) | 2012-08-30 | — | — | US | disclosed |
| WO-2011051906-A1 | METHOD FOR NATIVE LIGATION OF POLYPEPTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-05-05 | — | — | WO | disclosed |