⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025541 | 0.71 | — | — | |
| SCHEMBL26431148 | 0.71 | ADH1B (0.31) | — | |
| SCHEMBL23543063 | 0.69 | — | — | |
| SCHEMBL25947565 | 0.69 | — | — | |
| SCHEMBL6025538 | 0.69 | — | — | |
| SCHEMBL21531775 | 0.69 | — | — | |
| SCHEMBL925857 | 0.67 | — | — | |
| SCHEMBL20097095 | 0.67 | ADH1B (0.32) | — | |
| SCHEMBL23521071 | 0.67 | — | — | |
| SCHEMBL22590249 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | VANDERBILT UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-11814391-B2 | Macrocyclic compounds for the treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20200390099-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | UNIV VANDERBILT (US) | 2020-12-17 | — | — | US | disclosed |
| US-20180094071-A1 | ANTIGEN PRESENTING CELL TARGETED VACCINES | BAYLOR RESEARCH INSTITUTE | 2018-04-05 | — | — | US | disclosed |