Methane

Methane

SCHEMBL1900735

C.C.NC(O)=S.NC(O)=S.[NaH]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ATM Q13315 1/20 0.50
ATR Q13535 1/20 0.50
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
PTGS2 P35354 1/20 0.36
HPGD P15428 1/20 0.36
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL1442993 1.00 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL8628682 1.00
Methane SCHEMBL11037799 1.00 TSHR (0.50) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL9769006 0.95 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
SCHEMBL7198648 0.94 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10
SCHEMBL27509881 0.94
SCHEMBL8014988 0.94 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10
SCHEMBL451238 0.94
Methane SCHEMBL8838996 0.94 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL11423626 0.94 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200164341-A1 METHOD OF MAKING A MERCURY SORBENT AMCOL INTERNATIONAL CORP (US) 2020-05-28 US claimed
US-20180304229-A1 IMPROVED METHOD OF MAKING A MERCURY SORBENT AMCOL INTERNATIONAL CORPORATION (US) 2018-10-25 US claimed
EP-3368210-A1 IMPROVED METHOD OF MAKING A MERCURY SORBENT Amcol International Corporation (US) 2018-09-05 EP claimed
EP-1259577-B1 PROCESS FOR REMOVING MERCURY FROM HYDROCARBONS UNION OIL CO (US) 2007-03-21 EP claimed
US-20030116475-A1 Process for removing mercury from liquid hydrocarbons using a sulfur-containing organic compound FRANKIEWICZ THEODORE C (US) 2003-06-26 US claimed
US-6537443-B1 Removing colloids and treating with organic or inorganic sulfur containing compound such as an alkali or alkaline earth sulfide, dithiocarbamate or sulfurized isobutylene UNION OIL COMPANY OF CALIFORNIA 2003-03-25 US claimed
EP-1259577-A1 PROCESS FOR REMOVING MERCURY FROM HYDROCARBONS UNION OIL COMPANY OF CALIFORNIA (US) 2002-11-27 EP claimed
WO-2001062870-A1 PROCESS FOR REMOVING MERCURY FROM HYDROCARBONS UNION OIL COMPANY OF CALIFORNIA (US) 2001-08-30 WO claimed
EP-0972651-A1 Image enhancing compositions Xerox Corporation (US) 2000-01-19 EP claimed
WO-1999034926-A1 METHOD FOR RECOVERING AND SEPARATING METALS FROM WASTE STREAMS KREISLER LAWRENCE (US) 1999-07-15 WO claimed
US-5746814-A Decurling compositions XEROX CORPORATION (US) 1998-05-05 US claimed
JP-58067874-A None JP disclosed
US-20230133044-A1 THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS BROWN DENNIS M (US) 2023-05-04 US disclosed
US-11541027-B2 Use of dianhydrogalactitol and analogs or derivatives thereof in combination with platinum-containing antineoplastic agents to treat non-small-cell carcinoma of the lung and brain metastases DEL MAR PHARMACEUTICALS (BC) LTD. (CA) 2023-01-03 US disclosed
US-11026914-B2 Use of dianhydrogalactitol and analogs and derivatives thereof to treat recurrent malignant glioma or progressive secondary brain tumor DEL MAR PHARMACEUTICALS (BC) LTD. (CA) 2021-06-08 US disclosed
US-4324799-A Fungicidal thioglycolic acid anilides, processes for their manufacture and pesticidal compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4317758-A SULFUR CONATING COMPOUNDS DISSOLVED IN A MODIFIED ACRYLAMIDE POLYMER PHILLIPS PETROLEUM COMPANY (US) 1982-03-02 US disclosed
EP-0039083-A1 Viscosity-stabilized aqueous acrylamide polymer solutions and use of viscosity stabilizer compounds PHILLIPS PETROLEUM COMPANY (US) 1981-11-04 EP disclosed
US-4086339-A OF N,N-DIMETHYL-DITHIOCARBAMATE AND 8-HYDROXY-QUINOLINE; FUNGICIDES, BACTERICIDES ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) 1978-04-25 US disclosed
US-3962304-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133044-A1 THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS UNG, DPYD, TPMT TSHR 4307/4885ATM 2664/4885ATR 2199/4885
US-11026914-B2 Use of dianhydrogalactitol and analogs and derivatives thereof to treat recurrent malignant glioma or progressive secondary brain tumor DDOST, DAD1, PHGDH TSHR 2676/4885ATM 1963/4885ATR 1731/4885
US-11541027-B2 Use of dianhydrogalactitol and analogs or derivatives thereof in combination with platinum-containing antineoplastic agents to treat non-small-cell carcinoma of the lung and brain metastases DNMT1, MGMT, DCK TSHR 3563/4885ATM 29/4885ATR 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.