SCHEMBL19007368

SCHEMBL19007368

COc1ccccc1OC(=O)c1ccc(C=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
PRSS1 P07477 1/20 0.60
ACR P10323 1/20 0.60
MAPT P10636 2/20 0.59
KDM4E B2RXH2 1/20 0.59
TSHR P16473 3/20 0.50
SYK P43405 1/20 0.50
VCP P55072 1/20 0.50
KMT2A Q03164 5/20 0.48
MEN1 O00255 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
POLB P06746 2/20 0.48
CYP3A4 P08684 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SLC6A3 Q01959 1/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
HPGD P15428 2/20 0.47
BRAF P15056 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12520418 0.88 PRSS1 (0.73) PRSS1ACRMAPTTSHRKMT2A
SCHEMBL19218162 0.86 ALDH1A1 (0.80) ALDH1A1MAPTKDM4ETSHRSYK
SCHEMBL25167795 0.84 ALDH1A1 (0.82) ALDH1A1MAPTKDM4ETSHRSYK
SCHEMBL8393499 0.83 ALDH1A1 (0.75) ALDH1A1MAPTKDM4ETSHRSYK
SCHEMBL7334832 0.83 ALDH1A1 (0.67) ALDH1A1MAPTKDM4ETSHRSYK
SCHEMBL16838267 0.83 MAPT (0.72) ALDH1A1PRSS1ACRMAPTTSHR
SCHEMBL1671519 0.83 PRSS1 (0.66) ALDH1A1PRSS1ACRMAPTTSHR
SCHEMBL29749397 0.83 PRSS1 (0.66) ALDH1A1PRSS1ACRMAPTTSHR
SCHEMBL19214414 0.82 ALDH1A1 (0.66) ALDH1A1MAPTKDM4ETSHRSYK
SCHEMBL8210665 0.81 PRSS1 (0.65) ALDH1A1PRSS1ACRMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181608-A1 AN EPOXY RESIN CURING AGENT AND PREPARATION METHODS AND USES THEREOF Guangdong Guangshan New Materials Co., Ltd. (CN) 2017-06-21 EP disclosed