Ether

Ether

SCHEMBL1900760

CCOCC.O=C(O)c1ccc(-c2ccc(C(=O)O)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 1/20 0.49
KDM4E B2RXH2 2/20 0.47
GFER P55789 1/20 0.47
KMT2A Q03164 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
MCL1 Q07820 4/20 0.46
ALDH1A1 P00352 1/20 0.46
RARB P10826 4/20 0.44
RARA P10276 2/20 0.44
PTPN11 Q06124 2/20 0.43
ACMSD Q8TDX5 3/20 0.43
HNF4A P41235 2/20 0.43
DHFR P00374 1/20 0.43
DCLRE1A Q6PJP8 1/20 0.42
DCLRE1B Q9H816 1/20 0.42
RARG P13631 1/20 0.42
POLB P06746 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
LCK P06239 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL21878444 0.92 PTPN11 (0.55) MCL1RARBPTPN11RXRARXRB
Ether SCHEMBL21878437 0.87 PTPN11 (0.59) PTPN11DCLRE1ADCLRE1BRXRARXRB
Butane SCHEMBL15105387 0.86 MCL1 (0.54) CFDKDM4EGFERKMT2ARXFP1
Ether SCHEMBL2811983 0.85 RARB (0.57) CFDMCL1RARBRARAPTPN11
Ether SCHEMBL11626579 0.84 KDM4E (0.72) CFDKDM4EGFERKMT2ARXFP1
Pyromellitic Acid SCHEMBL14353395 0.83 TSHR (0.47) CFDKDM4EKMT2AALDH1A1POLB
SCHEMBL30690398 0.83 KMT2A (0.62) CFDKDM4EGFERKMT2ARXFP1
SCHEMBL30690397 0.83 KMT2A (0.62) CFDKDM4EGFERKMT2ARXFP1
SCHEMBL33365 0.83 KMT2A (0.62) CFDKDM4EGFERKMT2ARXFP1
SCHEMBL5886273 0.82 TSHR (0.55) CFDKDM4EKMT2AMCL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2322960-A1 Optical film, polarizer and liquid crystal display JSR Corporation (JP) 2011-05-18 EP disclosed
US-20090231518-A1 OPTICAL FILM, POLARIZATION PLATE AND LIQUID CRYSTAL DISPALY JSR CORPORATION (JP) 2009-09-17 US disclosed
US-20080151373-A1 Optical Film, Polarizing Plate and Liquid Crystal Display JSR CORPORATION (JP) 2008-06-26 US disclosed
EP-1785753-A1 OPTICAL FILM, POLARIZATION PLATE AND LIQUID CRYSTAL DISPLAY JSR Corporation (JP) 2007-05-16 EP disclosed
EP-1780562-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY JSR Corporation (JP) 2007-05-02 EP disclosed
EP-0499159-B1 Liquid crystal device and dislay apparatus CANON KK (JP) 1997-05-07 EP disclosed
US-5419932-A Polyamide alignment film CANON KABUSHIKI KAISHA (JP) 1995-05-30 US disclosed
EP-0499159-A2 Liquid crystal device and dislay apparatus CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
US-4965339-A CYCLIZATION OF A POLYAMIC ACID HAVING PERFLUOROALKYL GROUPS IN A SOLVENT IN THE PRSENCE OF A LOWER FATTY MONCARBOXYLIC ACID ANHYDRIDE AND A TERTIARY AMINE; COATINGS; FILMS CENTRAL GLASS COMPANY, LIMITED (JP) 1990-10-23 US disclosed