Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.57 |
| ▸ | RXRB | P28702 | 3/20 | 0.57 |
| ▸ | RXRA | P19793 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498034 | 0.87 | RXRB (0.70) | RARBRXRBRXRAMCL1PDE4A | |
| SCHEMBL29771992 | 0.87 | RXRB (0.70) | RARBRXRBRXRAMCL1PDE4A | |
| Ether SCHEMBL1900760 | 0.85 | CFD (0.49) | RARBRXRBRXRAMCL1RARA | |
| Hydrochloric Acid SCHEMBL4365452 | 0.85 | RXRB (0.68) | RARBRXRBRXRAMCL1PDE4A | |
| Hydrochloric Acid SCHEMBL9150803 | 0.85 | RXRB (0.68) | RARBRXRBRXRAMCL1PDE4A | |
| SCHEMBL17177748 | 0.83 | RXRB (0.71) | RARBRXRBRXRAMCL1PDE4A | |
| Ether SCHEMBL21878444 | 0.81 | PTPN11 (0.55) | RARBRXRBRXRAMCL1PTPN11 | |
| SCHEMBL20556331 | 0.81 | RARB (0.68) | RARBRXRBRXRAMCL1PDE4A | |
| SCHEMBL2811988 | 0.80 | RXRB (0.63) | RARBRXRBRXRAMCL1PDE4A | |
| SCHEMBL8840571 | 0.79 | MCL1 (0.65) | RARBRXRBRXRAMCL1HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | RARB 2349/4885RXRB 1440/4885RXRA 1635/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | RARB 4194/4885RXRB 3514/4885RXRA 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.