SCHEMBL19007871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19797075	0.92	CA1 (0.32)	CA1CA2TSHRCYP2C9DGAT1
	SCHEMBL19796397	0.91	TSHR (0.38)	CA1CA2TSHRCYP2C9RAB9A
	SCHEMBL19796609	0.91	CNR2 (0.38)	CA1CA2TSHRCYP2C9DGAT1
	SCHEMBL19797113	0.90	SPHK1 (0.37)	CA1CA2TSHRCYP2C9SPHK1
	SCHEMBL19796651	0.90	FPR2 (0.36)	CA1CA2TSHRCYP2C9DGAT1
	SCHEMBL19797085	0.89	SPHK1 (0.38)	TSHRCYP2C9SPHK1
	SCHEMBL19797111	0.89	SPHK1 (0.38)	TSHRCYP2C9SPHK1
	SCHEMBL19796861	0.89	CA1 (0.33)	CA1CA2TSHRCYP2C9DGAT1
	SCHEMBL19796851	0.89	TSHR (0.36)	CA1CA2TSHRMAPTCNR1
	SCHEMBL19796585	0.88	CNR2 (0.36)	CA1CA2TSHRCYP2C9DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.