Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695540 | 0.87 | NPC1 (0.54) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL11695545 | 0.87 | NPC1 (0.54) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL22755750 | 0.81 | NPC1 (0.59) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL3950942 | 0.80 | TDP1 (0.44) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL11020065 | 0.79 | TDP1 (0.44) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL11022109 | 0.79 | TDP1 (0.44) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL11139922 | 0.74 | KMT2A (0.52) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL11139916 | 0.74 | KMT2A (0.52) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL1485807 | 0.73 | TDP1 (0.42) | NPC1MAPTRAB9AL3MBTL1MAPK1 | |
| SCHEMBL2662650 | 0.73 | GAA (0.45) | NPC1MAPTRAB9AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214781-A1 | COSMETIC COMPOSITIONS COMPRISING DRAGLINE SPIDER SILK | SEEVIX MATERIAL SCIENCES LTD. (IL) | 2021-10-28 | — | — | WO | disclosed |
| US-9988333-B2 | Process for making 2,5-dihalogenated phenol | BASF SE (DE) | 2018-06-05 | — | — | US | disclosed |
| US-20170174603-A1 | Process for Making 2,5-Dihalogenated Phenol | BASF SE (DE) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174603-A1 | Process for Making 2,5-Dihalogenated Phenol | TYR, CA4, CA6 | NPC1 3826/4885MAPT 2265/4885RAB9A 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.