Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151796 | 0.84 | UGT2B7 (0.73) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrogen Peroxide SCHEMBL8096014 | 0.80 | UGT2B7 (0.72) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL2483568 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL12581063 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL791742 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL16174384 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL8230082 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL16172571 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL12435784 | 0.80 | KDM4E (0.62) | SLC6A4CYP2D6CYP3A4MEN1KMT2A | |
| SCHEMBL5032107 | 0.79 | UGT2B7 (0.66) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056788-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-05-12 | — | — | WO | claimed |
| US-20120220665-A1 | Inhibiting Neurotransmitter Reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2011056788-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-05-12 | — | — | WO | disclosed |