⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59011 | 0.92 | — | — | |
| SCHEMBL988233 | 0.89 | ALDH1A1 (0.34) | — | |
| SCHEMBL3836869 | 0.89 | ALDH1A1 (0.34) | — | |
| SCHEMBL988655 | 0.89 | ALDH1A1 (0.34) | — | |
| SCHEMBL126411 | 0.89 | ALDH1A1 (0.34) | — | |
| SCHEMBL6654919 | 0.89 | ALDH1A1 (0.34) | — | |
| SCHEMBL6651287 | 0.89 | ALDH1A1 (0.34) | — | |
| SCHEMBL6650214 | 0.85 | EPHX2 (0.34) | — | |
| SCHEMBL8698269 | 0.83 | EPHX2 (0.33) | — | |
| SCHEMBL19316 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548900-B2 | Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-01-10 | — | — | US | claimed |
| CN-112442045-B | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2022-02-18 | — | — | CN | claimed |
| EP-3760633-B1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2021-12-15 | — | — | EP | claimed |
| US-10959987-B2 | Imidazole-based compounds as hepatitis C virus inhibitors | KING ABDULAZIZ UNIVERSITY (SA) | 2021-03-30 | — | — | US | claimed |
| CN-110229171-B | Oxazinoquinazoline and oxazinoquinoline compound and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-112442045-A | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2021-03-05 | — | — | CN | claimed |
| US-20210040114-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF | ACCSALUS BIOSCIENCES LIMITED (VG) | 2021-02-11 | — | — | US | claimed |
| EP-3760633-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-01-06 | — | — | EP | claimed |
| CN-110229172-B | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2020-12-25 | — | — | CN | claimed |
| US-20200323822-A1 | IMIDAZOLE-BASED COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | KING ABDULAZIZ UNIVERSITY (SA) | 2020-10-15 | — | — | US | claimed |
| US-20030018041-A1 | Spiroindene and spiroindane compounds | PURDUE PHARMA L.P. | 2003-01-23 | — | — | US | claimed |
| US-20030013874-A1 | Nociceptin analogs | PURDUE PHARMA L.P | 2003-01-16 | — | — | US | claimed |
| US-20030008886-A1 | Benzimidazolone compounds | PURDUE PHARMA L.P. | 2003-01-09 | — | — | US | claimed |
| WO-2002085357-A1 | NOCICEPTIN ANALOGS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| WO-2002085355-A1 | SPIROPYRAZOLE COMPOUNDS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| WO-2002085354-A1 | SPIROINDENE AND SPIROINDANE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| WO-2002085291-A2 | NOCICEPTIN ANALOGS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| WO-2002085361-A1 | BENZIMIDAZOLONE COMPOUNDS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| US-4648898-A | DIAMINO-DIFLUOROMETHYLTHIOTRIAZINES | SHIONOGI & CO., LTD. (JP) | 1987-03-10 | — | — | US | claimed |
| US-3933800-A | O-SUBSTITUTED OXIMES, MICROBIOCIDES | GRUPPO LEPETIT S.P.A. (IT) | 1976-01-20 | — | — | US | claimed |