SCHEMBL19009449

SCHEMBL19009449

CCc1nc2ccccc2c2cnc3ccccc3c12

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.47
GPR3 P46089 2/20 0.47
POLB P06746 1/20 0.44
RAD52 P43351 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 3/20 0.43
PDPK1 O15530 1/20 0.41
GAA P10253 2/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
MAPK1 P28482 2/20 0.40
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TOP2A P11388 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TNKS2 Q9H2K2 1/20 0.38
MEN1 O00255 2/20 0.37
TLR7 Q9NYK1 2/20 0.37
ACP1 P24666 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19051729 0.82 POLB (0.49) KDM4EGPR3POLBRAD52SMN1; SMN2
SCHEMBL19009455 0.78 POLB (0.45) KDM4EGPR3POLBRAD52SMN1; SMN2
SCHEMBL19051731 0.78 NPSR1 (0.46) KDM4EPOLBRAD52SMN1; SMN2KMT2A
SCHEMBL12533981 0.76 KMT2A (0.64) KDM4EGPR3POLBRAD52SMN1; SMN2
SCHEMBL5213764 0.75 POLB (0.45) KDM4EGPR3POLBRAD52SMN1; SMN2
SCHEMBL17997989 0.74 KDM4E (0.44) KDM4EGPR3POLBRAD52SMN1; SMN2
SCHEMBL18748049 0.72 POLB (0.50) KDM4EPOLBRAD52SMN1; SMN2KMT2A
SCHEMBL16535871 0.72 GPR3 (0.52) KDM4EGPR3SMN1; SMN2PDPK1ALDH1A1
SCHEMBL17036576 0.71 POLB (0.49) KDM4EPOLBRAD52SMN1; SMN2KMT2A
SCHEMBL19020845 0.71 GPR3 (0.68) KDM4EGPR3SMN1; SMN2PDPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed