SCHEMBL19009633

SCHEMBL19009633

c1ccc(-c2nc3c(cc(-c4cccc(-c5ccc6ccccc6c5)c4)c4cccnc43)c3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.42
ADORA1 P30542 3/20 0.42
CYP11B1 P15538 2/20 0.40
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B2 P19099 1/20 0.40
PIK3CD O00329 1/20 0.39
SIRT2 Q8IXJ6 2/20 0.37
CCR1 P32246 3/20 0.37
CCR8 P51685 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
HTR2B P41595 1/20 0.35
HTR5A P47898 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009646 0.89 CYP11B1 (0.35) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL21537673 0.84 CCR1 (0.38) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL12761839 0.84 ADORA2A (0.50) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL27934158 0.82 CCR1 (0.46) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL9976748 0.82 CCR1 (0.48) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL21757067 0.81 CCR1 (0.40) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL9976763 0.81 CYP17A1 (0.45) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL21537674 0.80 CYP11B1 (0.40) CYP11B1PIK3CDCCR1CCR8L3MBTL1
SCHEMBL21757138 0.80 CCR1 (0.39) ADORA2AADORA1CYP11B1CYP17A1CYP19A1
SCHEMBL20726858 0.79 CCR1 (0.44) ADORA2AADORA1CYP11B1CYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed