Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976748 | 0.95 | CCR1 (0.48) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL27934158 | 0.92 | CCR1 (0.46) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL9976752 | 0.84 | TOP1 (0.49) | CCR1CCR8HSP90AA1MMP2NPC1 | |
| SCHEMBL15496959 | 0.84 | CYP11B1 (0.42) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL12831011 | 0.83 | HTR2B (0.34) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL28809041 | 0.83 | ALDH1A1 (0.56) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL29720563 | 0.83 | ALDH1A1 (0.56) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL12577950 | 0.83 | CYP11B1 (0.38) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL12577892 | 0.83 | GPR84 (0.39) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 | |
| SCHEMBL14478694 | 0.82 | ALDH1A1 (0.42) | CYP17A1CYP19A1CYP11B1CYP11B2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877354-B2 | Heterocyclic compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8877354-B2 | Heterocyclic compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20120153270-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120153270-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120153270-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | ORC3, CYP1A1, CRY1 | CYP17A1 395/4885CYP19A1 14/4885CYP11B1 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.