Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818349 | 0.89 | GRM5 (0.39) | GRM5DRD1 | |
| SCHEMBL726239 | 0.89 | GRM5 (0.39) | GRM5DRD1 | |
| SCHEMBL19912184 | 0.84 | TNKS (0.34) | GRM5 | |
| SCHEMBL15905925 | 0.83 | GRM5 (0.36) | GRM5DRD1 | |
| SCHEMBL13681621 | 0.78 | SCN9A (0.37) | GRM5 | |
| SCHEMBL14688030 | 0.78 | DRD1 (0.41) | DRD1 | |
| SCHEMBL1224769 | 0.75 | CYP11B1 (0.33) | GRM5DRD1 | |
| SCHEMBL12446372 | 0.72 | PTGER3 (0.36) | GRM5DRD1 | |
| SCHEMBL16361843 | 0.71 | DRD1 (0.43) | DRD1 | |
| SCHEMBL14271036 | 0.70 | HTR1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | POF1B, FGFR1, COASY | GRM5 1714/4885DRD1 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.