Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904122 | 0.91 | NAMPT (0.43) | NAMPTEHMT2MASP2L3MBTL1HPGD | |
| SCHEMBL1906806 | 0.91 | NAMPT (0.43) | NAMPTEHMT2MASP2L3MBTL1HPGD | |
| SCHEMBL1901340 | 0.89 | PDPK1 (0.39) | NAMPTEHMT2MASP2TLR2FURIN | |
| SCHEMBL1902789 | 0.86 | NAMPT (0.44) | NAMPTEHMT2MASP2L3MBTL1MEN1 | |
| SCHEMBL1432861 | 0.84 | NAMPT (0.43) | NAMPTEHMT2MASP2L3MBTL1HPGD | |
| SCHEMBL1904701 | 0.84 | NAMPT (0.45) | NAMPTEHMT2MASP2L3MBTL1HPGD | |
| SCHEMBL1431865 | 0.84 | NAMPT (0.45) | NAMPTEHMT2MASP2L3MBTL1HPGD | |
| SCHEMBL1432011 | 0.84 | NAMPT (0.45) | NAMPTEHMT2MASP2L3MBTL1HPGD | |
| SCHEMBL1904386 | 0.84 | NAMPT (0.45) | NAMPTEHMT2MASP2L3MBTL1MEN1 | |
| SCHEMBL1432651 | 0.83 | NAMPT (0.46) | NAMPTEHMT2MASP2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |