SCHEMBL1901396

SCHEMBL1901396

C=CCOc1c(C)cccc1[Si](C)(C)C1c2cc(-c3ccccc3C)ccc2-c2ccc(-c3ccccc3C)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.36
CXCR5 P32302 1/20 0.35
MAPT P10636 1/20 0.33
MGAM O43451 2/20 0.33
GAA P10253 2/20 0.33
SI P14410 2/20 0.33
MGAM2 Q2M2H8 2/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
LCK P06239 1/20 0.32
KDR P35968 1/20 0.32
JAK3 P52333 1/20 0.32
MAPK14 Q16539 1/20 0.32
HTR7 P34969 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
ALDH1A1 P00352 3/20 0.31
CYP1A2 P05177 3/20 0.31
CYP3A4 P08684 3/20 0.31
CYP2D6 P10635 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902985 0.91 CXCR5 (0.35) CXCR5MAPTALOX5APFEN1ALDH1A1
SCHEMBL1907820 0.91 HTR2C (0.34) HTR2CCXCR5MAPTMGAMGAA
SCHEMBL1906558 0.90 CXCR5 (0.32) HTR2CCXCR5MAPTALDH1A1TRPA1
SCHEMBL1905962 0.90 HTR2C (0.35) HTR2CCXCR5MAPTMGAMGAA
SCHEMBL1908095 0.89 CXCR5 (0.33) CXCR5MGAMGAASIMGAM2
SCHEMBL6191676 0.89 CXCR5 (0.39) CXCR5MAPTGAAALDH1A1CYP3A4
SCHEMBL1903363 0.88 HTR2C (0.34) HTR2CCXCR5MGAMGAASI
SCHEMBL1907787 0.88 MYB (0.35) HTR2CMAPTMGAMGAASI
SCHEMBL1907808 0.88 HTR2C (0.39) HTR2CMAPTALOX5APFEN1LCK
SCHEMBL1906374 0.88 HTR2C (0.34) HTR2CMAPTMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110118427-A1 Transition Metal Complex And Process For Production Thereof, Olefin Polymerization Catalyst, Process For Production of Polyolefin Resin, And Substituted Fluorene Compound And Process For Production Thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118427-A1 Transition Metal Complex And Process For Production Thereof, Olefin Polymerization Catalyst, Process For Production of Polyolefin Resin, And Substituted Fluorene Compound And Process For Production Thereof FIP1L1, FDFT1, COASY HTR2C 4752/4885CXCR5 4074/4885MAPT 1329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.