Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015031 | 0.95 | MAPT (0.35) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19015130 | 0.95 | TDP1 (0.33) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19015035 | 0.90 | KMT2A (0.34) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19014797 | 0.88 | TDP1 (0.37) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19015036 | 0.86 | — | — | |
| SCHEMBL19015033 | 0.84 | ALDH1A1 (0.32) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19014908 | 0.84 | KMT2A (0.32) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL18069152 | 0.84 | MAPT (0.40) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19015039 | 0.84 | TDP1 (0.40) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL19014825 | 0.84 | TDP1 (0.38) | ALDH1A1KMT2AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |