Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 4/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015073 | 0.81 | LMNA (0.32) | MCL1ALDH1A1KDM4EHPGDBCL2 | |
| SCHEMBL17617811 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL19014926 | 0.79 | PRMT1 (0.39) | ALDH1A1KDM4EHPGDBCL2PRMT1 | |
| SCHEMBL17617836 | 0.76 | KMT2A (0.43) | ALDH1A1KDM4EHPGDBCL2PRMT1 | |
| SCHEMBL17617827 | 0.76 | KMT2A (0.56) | MCL1ALDH1A1KDM4EHPGDBCL2 | |
| SCHEMBL17617826 | 0.75 | POLB (0.55) | ALDH1A1KDM4EHPGDBCL2PRMT1 | |
| SCHEMBL19015163 | 0.75 | KMT2A (0.38) | MCL1ALDH1A1KDM4EHPGDBCL2 | |
| SCHEMBL17617805 | 0.73 | KMT2A (0.42) | ALDH1A1KDM4EHPGDBCL2PRMT1 | |
| SCHEMBL19015159 | 0.72 | TYMS (0.34) | MCL1ALDH1A1KDM4EHPGDBCL2 | |
| SCHEMBL19015059 | 0.72 | PRMT1 (0.33) | ALDH1A1KDM4EPRMT1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |