Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 1.00 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | GMNN | O75496 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | CETP | P11597 | 3/20 | 1.00 |
| ▸ | UBE2N | P61088 | 3/20 | 1.00 |
| ▸ | THPO | P40225 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907293 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| SCHEMBL18127645 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| Dihydrospingosine SCHEMBL7106054 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| SCHEMBL8746720 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| Dihydrospingosine SCHEMBL3509781 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| Dihydrospingosine SCHEMBL13285654 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| Dihydrospingosine SCHEMBL1905632 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| SCHEMBL21660227 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| SCHEMBL21431064 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN | |
| SCHEMBL12330726 | 1.00 | CYP2D6 (1.00) | CYP2D6SPHK1LMNAMAPTGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024219793-A1 | MARKER FOR PREDICTING GROWTH RATE OF UTERINE FIBROIDS, AND USE THEREOF | 한국 한의학 연구원 | 2024-10-24 | — | — | WO | claimed |
| EP-3773919-A1 | METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS | Pepsis Limited (GB) | 2021-02-17 | — | — | EP | claimed |
| WO-2019186141-A1 | METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS | Pepsis Limited (GB) | 2019-10-03 | — | — | WO | claimed |
| EP-2424554-B1 | NOVEL SPHINGOSINE KINASE TYPE 1 INHIBITORS, COMPOSITIONS AND PROCESSES FOR USING SAME | ENZO THERAPEUTICS INC (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2024219793-A1 | MARKER FOR PREDICTING GROWTH RATE OF UTERINE FIBROIDS, AND USE THEREOF | 한국 한의학 연구원 | 2024-10-24 | — | — | WO | disclosed |
| WO-2024219793-A1 | MARKER FOR PREDICTING GROWTH RATE OF UTERINE FIBROIDS, AND USE THEREOF | 한국 한의학 연구원 | 2024-10-24 | — | — | WO | disclosed |
| US-20240210421-A1 | Methods of Predicting Atopic Dermatitis | NATIONAL JEWISH HEALTH | 2024-06-27 | — | — | US | disclosed |
| US-11529370-B2 | Use of composition comprising stem cell-derived exosome as effective ingredient in strengthening skin barrier and improving skin barrier function | EXOCOBIO INC. (KR) | 2022-12-20 | — | — | US | disclosed |
| EP-3773919-A1 | METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS | Pepsis Limited (GB) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019186141-A1 | METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS | Pepsis Limited (GB) | 2019-10-03 | — | — | WO | disclosed |
| US-20190117590-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | TEXAS TECH UNIVERSITY SYSTEM | 2019-04-25 | — | — | US | disclosed |
| EP-2669267-A1 | Compositions and methods for treating hyperproliferative disorders | TEXAS TECH UNIVERSITY (US) | 2013-12-04 | — | — | EP | disclosed |
| EP-2501672-A2 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISORDERS | TEXAS TECH UNIVERSITY (US) | 2012-09-26 | — | — | EP | disclosed |
| US-20110152267-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | TEXAS TECH UNIVERSITY SYSTEM | 2011-06-23 | — | — | US | disclosed |
| WO-2011060332-A2 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISORDERS | TEXAS TECH UNIVERSITY (US) | 2011-05-19 | — | — | WO | disclosed |
| US-7811602-B2 | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2010-10-12 | — | — | US | disclosed |
| EP-1750673-B1 | LIPOSOMAL FORMULATIONS COMPRISING DIHYDROSPHINGOMYELIN AND METHODS OF USE THEREOF | TEKMIRA PHARMACEUTICALS CORP (CA) | 2009-12-02 | — | — | EP | disclosed |
| EP-1750673-A2 | LIPOSOMAL FORMULATIONS COMPRISING DIHYDROSPHINGOMYELIN AND METHODS OF USE THEREOF | Inex Pharmaceuticals Corporation (CA) | 2007-02-14 | — | — | EP | disclosed |
| US-20060008909-A1 | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof | INEX PHARMACEUTICALS CORPORATION (CA) | 2006-01-12 | — | — | US | disclosed |
| WO-2005120461-A2 | LIPOSOMAL FORMULATIONS COMPRISING DIHYDROSPHINGOMYELIN AND METHODS OF USE THEREOF | INEX PHARMACEUTICALS CORPORATION (CA) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117590-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | SGMS1, S1PR1, SPHK1 | CYP2D6 4551/4885SPHK1 3/4885LMNA 1618/4885 |
| US-20110152267-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | SGMS1, S1PR1, SPHK1 | CYP2D6 4551/4885SPHK1 3/4885LMNA 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.