Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069165 | 0.85 | MEN1 (0.38) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL18069211 | 0.83 | KMT2A (0.38) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19014908 | 0.83 | KMT2A (0.32) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19015149 | 0.81 | TDP1 (0.37) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19015026 | 0.81 | TDP1 (0.37) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19015027 | 0.81 | TDP1 (0.37) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19014825 | 0.81 | TDP1 (0.38) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19014823 | 0.80 | TDP1 (0.33) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19014911 | 0.80 | TDP1 (0.39) | TDP1MAPTHTTKMT2APOLB | |
| SCHEMBL19015130 | 0.79 | TDP1 (0.33) | TDP1MAPTHTTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |