Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069173 | 0.86 | MAPT (0.39) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL18069214 | 0.84 | MAPT (0.40) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19014911 | 0.84 | TDP1 (0.39) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19015040 | 0.84 | TDP1 (0.34) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19015026 | 0.83 | TDP1 (0.37) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19015027 | 0.83 | TDP1 (0.37) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19015149 | 0.83 | TDP1 (0.37) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19014825 | 0.81 | TDP1 (0.38) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19015136 | 0.80 | TDP1 (0.33) | TDP1MAPTKMT2AHTTALDH1A1 | |
| SCHEMBL19015130 | 0.80 | TDP1 (0.33) | TDP1MAPTKMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |